MiRisten for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
A Phase 1 Trial of miRisten in Adult Patients With Relapsed/Refractory AML
City of Hope Medical Center
12 participants
Oct 24, 2025
INTERVENTIONAL
Conditions
Summary
This phase I trial tests the safety, side effects, and best dose of miRisten in treating patients with acute myeloid leukemia (AML) that has come back after a period of improvement (relapsed) or that has not responded to previous treatment (refractory). MiRisten may stop the growth of cancer cells by blocking some of the molecules needed for cell growth. Giving miRisten may be safe, tolerable and/or effective in treating patients with relapsed or refractory AML.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
Undergo bone marrow and blood sample collection
Undergo ECHO
Given IV
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07025564