RecruitingNCT07027306

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures: An International Multicenter Prospective Study


Sponsor

AO Foundation, AO Spine

Enrollment

648 participants

Start Date

Mar 19, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

This is an international multicenter prospective observational study. Patients with radiologically confirmed, symptomatic, single- or multilevel contiguous TL (from T1 to L5) fractures as a result of primary osteoporosis will be recruited from participating clinics/hospitals (ie, study sites). Fractures included are insufficiency fractures (confirmed by magnetic resonance imaging \[MRI\]) and traumatic fractures (low-energy trauma, confirmed by computed tomography \[CT\] or MRI).


Eligibility

Min Age: 50 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Posterior stabilization (pedicle screws) for people with osteoporosis and osteoporotic fractures. The study is currently recruiting participants at 15 locations. People eligible for this study include aged 50 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREPosterior stabilization (pedicle screws)

* Any other type of solely vertebral augmentation (stents, etc.), specify * Posterior stabilization (pedicle screws) * Posterior stabilization (pedicle screws) with kyphoplasty/vertebroplasty * Posterior stabilization (pedicle screws) with screw augmentation * Posterior stabilization (pedicle screws) with screw augmentation and kyphoplasty/vertebroplasty * Posterior stabilization (pedicle screws) with vertebral osteotomy (pedicle subtraction osteotomy or similar) * Combined posterior and anterior stabilization


Locations(15)

University of California San Francisco (USCF) Department of Orthopaedic Surgery

San Francisco, California, United States

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

Sanatorio Güemes

Buenos Aires, Argentina

Cajuru University Hospital

Curitiba, Brazil

Department of Orthopedic Surgery, Clinica Alemana de Santiago

Santiago, Chile

Orthopaedic Department, Assiut University Hospitals, Faculty of Medicine

Asyut, Egypt

Tampere University Hospital

Tampere, Finland

Center for Spinal and Scoliosis Surgery, Malteser Waldkrankenhaus St. Marien

Erlangen, Germany

PGIMER - Postgraduate Institute of Medical Education and Research

Chandigarh, India

Dokkyo Medical University Hospital

Tochigi, Japan

Island Hospital Spine Centre

George Town, Malaysia

Spiatlul Clinic De Urgenta, "Profesor Doctor Nicolae Oblu"

Iași, Romania

Security Force Hospital

Riyāḑ, Saudi Arabia

Spital Emmental - Orthopädie Sonnenhof

Burgdorf, Switzerland

King's College Hospital

London, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT07027306


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