Osteoporosis Clinical Trials

156 recruitingLast updated: June 17, 2026

There are 156 actively recruiting osteoporosis clinical trials across 38 countries. Studies span Not Applicable, Phase 4, Phase 2, Phase 3. Top locations include Beijing, Beijing Municipality, China, Milan, Italy, Clermont-Ferrand, France. Updated daily from ClinicalTrials.gov.


Osteoporosis Trials at a Glance

156 actively recruiting trials for osteoporosis are listed on ClinicalTrialsFinder across 6 cities in 38 countries. The largest study group is Not Applicable with 46 trials, with the heaviest enrollment activity in Beijing, Milan, and Clermont-Ferrand. Lead sponsors running osteoporosis studies include National Taiwan University Hospital, Monash University, and Istituto Ortopedico Rizzoli.

Browse osteoporosis trials by phase

Treatments under study

About Osteoporosis Clinical Trials

Looking for clinical trials for Osteoporosis? There are currently 172 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Osteoporosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Osteoporosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 156 trials

Recruiting

Radiographic Cortical Thickness of the Humerus in Detecting Post-Stroke Regional Bone Loss

Dual-energy x-ray absorptiometryOsteoporosisHemiparesis After Stroke
Istanbul Physical Medicine Rehabilitation Training and Research Hospital65 enrolled1 locationNCT07651306
Recruiting
Not Applicable

U.S. Prospective Evaluation of EPIONE Device for Percutaneous MSK Procedures

OsteoporosisBone Tumortraumatic fracture
Precision IO Group60 enrolled3 locationsNCT07325578
Recruiting
Not Applicable

People With Osteoporosis Can Walk-BEST to Reduce Fall and Fracture Risk

Osteoporosis
McGill University Health Centre/Research Institute of the McGill University Health Centre28 enrolled1 locationNCT07621679
Recruiting
Not Applicable

Artificial Intelligence-Guided Diagnosis for High-Risk Osteoporosis Populations: A Pragmatic Randomized Clinical Trial

Osteoporosis
Taichung Veterans General Hospital1,180 enrolled3 locationsNCT07620834
Recruiting
Phase 4

GLP-1R Actions on Muscle and the Skeleton

ObesityOsteoporosisDrug Effect+2 more
Pennington Biomedical Research Center50 enrolled1 locationNCT07154719
Recruiting

Peripheral Mononuclear Cells to Screen, Monitor and Stratify the Population at Risk of Osteoporosis and Fractures

OsteoporosisOsteopeniaOsteoporosis Fracture
Istituto Ortopedico Rizzoli120 enrolled2 locationsNCT06551155
Recruiting
Not Applicable

MicroRNA and Markers and Therapeutic Response to Romosozumab and Abaloparatide in Postmenopausal Osteoporosis

MenopauseOsteoporosis
Istituto Auxologico Italiano42 enrolled2 locationsNCT07616401
Recruiting

Clinical Validation of BBCT-hip

Osteoporosis
Istituto Ortopedico Rizzoli300 enrolled2 locationsNCT06270758
Recruiting
Not Applicable

Mode of Exercise and Bone Biomarkers in Older Veterans

OsteoporosisMusculoskeletal DiseasesAging
VA Office of Research and Development120 enrolled1 locationNCT05266976
Recruiting
Phase 2

TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status

pre frailtySarcopeniaOsteoporosis+2 more
Tri-Service General Hospital90 enrolled1 locationNCT07597850
Recruiting
Not Applicable

Resting-state Imaging and OSteoporosiS

Osteoporosis
University Hospital, Clermont-Ferrand66 enrolled1 locationNCT07030205
Recruiting
Not Applicable

RESTORE - Study of AGN1 LOEP to Prevent Secondary Hip Fractures

OsteoporosisHip FracturesFragility Fracture
AgNovos Healthcare, LLC2,400 enrolled66 locationsNCT04796350
Recruiting

The Osteoporotic Fracture Classification-based Scoring System for Treatment Decision in Thoracolumbar Osteoporotic Fractures

OsteoporosisOsteoporotic Fractures
AO Foundation, AO Spine648 enrolled15 locationsNCT07027306
Recruiting

Atypical Fracture Cohort Study

Atypical Femur FractureAtypical Subtrochanteric FractureOsteoporosis With AFf
University Health Network, Toronto300 enrolled3 locationsNCT01747291
Recruiting

Self-questionnaire in Osteoporosis

Osteoporosis
CHU de Quebec-Universite Laval58 enrolled1 locationNCT07067827
Recruiting
Phase 2

A Phase II Clinical Trial of the Safety and Efficacy of SAL056 at Different Doses and Dosing Regimens

postmenopausal women with osteoporosis
Shenzhen Salubris Pharmaceuticals Co., Ltd.200 enrolled1 locationNCT07579936
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Heart FailureSarcopeniaOsteoporosis+11 more
Bettina Mittendorfer100 enrolled1 locationNCT07083557
Recruiting
Not Applicable

Contribution of Recreational Exercises to Balance and Muscle Strength in Osteoporosis Risk

Osteoporosis (Senile)
Suleyman Demirel University60 enrolled1 locationNCT07245355
Recruiting
Not Applicable

RESTORE: REducing Future fractureS and Improving ouTcOmes of fRagility fracturE

OsteoporosisFragility FractureOsteoporotic Fractures
University of Alabama at Birmingham2,634 enrolled23 locationsNCT06455085
Recruiting
Not Applicable

Clinical Relevance of Modifying RANKL Signaling During Folliculogenesis

OsteoporosisFemale InfertilityNF-κB Ligand+2 more
Peter Humaidan100 enrolled1 locationNCT07546552