RecruitingNot ApplicableNCT07028216

Mindful Self-compassion for Anxiety and Depression: Impact of Delivery Method

Mindful Self-Compassion for Anxiety and Depression: A Randomized Comparison of In-Person Versus Videoconference Delivery


Sponsor

Georgetown University

Enrollment

80 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The study will compare the delivery of an 8-week Mindful Self-Compassion training, in-person against video-conference, on anxiety and depression symptom severity in patients with diagnosed anxiety disorders (generalized anxiety disorder, social anxiety disorder, and panic disorder) or major depressive disorder or dysthymia.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria4

  • Must have a primary anxiety disorder (social anxiety disorder, generalized anxiety disorder, panic disorder, or agoraphobia) or major depressive disorder, current
  • Must score low on self-compassion, as measured by the self-compassion scale
  • Must understand study procedure and willing to participate in all testing visits, and treatment as assigned
  • Must be able to give informed consent to the study procedures

Exclusion Criteria13

  • Comorbid psychiatric disorder other than anxiety or depression, such as psychotic disorder, obsessive compulsive disorder, eating disorders (i.e., anorexia and bulimia), bipolar disorder; developmental or organic mental disorders; and current (past 6 months) substance use disorders and current post-traumatic stress disorder as assessed by clinician at screening visit
  • A serious medical condition that may result in surgery or hospitalization.
  • A history of head trauma causing prolonged loss of consciousness, or ongoing cognitive impairment
  • Inability to understand study procedures or informed consent process, or significant personality dysfunction likely to interfere with study participation (assessed during the clinical interview).
  • Subjects who will be non-compliant with the study procedures. This may include planned travel out of town.
  • Subjects taking some psychiatric medication such as barbiturates or antipsychotics. Sleep medications and some anti-depressants will be allowed, if the subject has been taken at stable dose 8 weeks prior to baseline and the patient plans to continue at the same dose through the trial.
  • Concurrent psychotherapy initiated within 1 month of screen interview, or ongoing psychotherapy of any duration directed specifically toward the treatment of anxiety (such as Cognitive Behavioral Therapy).
  • Individuals who have completed a course of MSC or an equivalent meditation training in the last year.
  • Individuals reporting significant active suicidal ideation or suicidal behaviors within the past year.
  • Individuals with a medical condition (i.e., epilepsy) that may be exacerbated by study treatment, as determined by a study physician or nurse practitioner based on history, physical, and/or labs.
  • Adults unable to consent
  • Pregnant women
  • Prisoners

Interventions

BEHAVIORALMindful Self-Compassion

The course teaching mindfulness meditation skills relevant to cultivating self-compassion.


Locations(1)

Georgetown University Medical Center

Washington D.C., District of Columbia, United States

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NCT07028216


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