Effect of a Liquid Tonic Drink on Post-meal Glucose and Insulin Responses
Examining the Efficacy of a Commercially Available Multi-ingredient Liquid Tonic Drink on Postprandial Glycemia in Men and Women With Overweight and/or Obesity.
Australian Catholic University
20 participants
Jul 8, 2025
INTERVENTIONAL
Conditions
Summary
A randomised, double blinded, placebo-controlled crossover design clinical trial conducted at the Mary MacKillop Institute for Health Research (MMIHR, Australian Catholic University) for individuals with overweight/ obesity. This study will measure the postprandial glucose and hormone responses to a high-carbohydrate meal with/ without a liquid tonic drink.
Eligibility
Inclusion Criteria2
- Aged ≥30-64 years
- Body Mass Index (BMI) of ≥27.0 kg/m2
Exclusion Criteria11
- younger than 30 or 65 years or older,
- a BMI less than 27.0 kg/m2,
- have an allergy to any of the components in the plant-based tonic (see section 6),
- pregnant or breastfeeding,
- regularly skipping breakfast (i.e. not consuming breakfast on 5/7 days per week),
- any diagnosed metabolic (e.g. diabetes), endocrine (e.g. hyperthyroidism), gastrointestinal (e.g. Crohn's) or cardiovascular (e.g. heart failure) abnormalities,
- on an energy-restricted diet; significant weight fluctuation in the previous 3 months (>5% body weight),
- high alcohol consumption (>14 units/week) (as per Alcohol Drink Guidelines),
- medication that is used to treat blood glucose,
- unable to attend in person testing sessions, or
- unable or unwilling to provide blood samples.
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Interventions
High-carbohydrate containing breakfast meal with the addition of the tonic drink
High-carbohydrate containing breakfast meal with the addition of the placebo drink
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07030010