Study of ALV-100 to Assess Safety, Tolerability, and PK/PD in Overweight/Obese Participants With or Without T2D

This early-stage study is testing a new investigational drug called ALV-100 in overweight or obese adults, with or without type 2 diabetes, to evaluate whether it is safe and how the body absorbs and uses it. The goal is to understand the drug's safety profile and early effects on blood sugar and body weight before larger trials are conducted. **You may be eligible if...** - You are between 18 and 65 years old - You have a BMI between 27 and 39.9 (overweight or obese) - Your body weight has been stable (within 5 kg) over the past 3 months - If female, you must not be able to become pregnant (surgically sterile or postmenopausal) **You may NOT be eligible if...** - You have type 1 diabetes or are on insulin - You have had recent significant weight loss through surgery or medication - You have serious heart, kidney, or liver disease - You have a recent history of eating disorders - You are pregnant, breastfeeding, or able to become pregnant Talk to your doctor to see if this trial is right for you.