Early Diagnosis of Pancreatic Cancer Duodenal Fluid-Based Biomarker Exploratory Study

This study is looking for early biomarkers (biological signals) of pancreatic cancer in fluid collected from the small intestine during routine upper endoscopy procedures, to improve early detection of this disease. **You may be eligible if:** - You are 19 or older - You are already scheduled for a gastroscopy (upper endoscopy), endoscopic ultrasound, or ERCP for a medical reason - You either have confirmed pancreatic cancer (any stage) OR are suspected to have it and are scheduled for a biopsy procedure - For the comparison group: you have a non-cancerous pancreas condition or no pancreatic disease **You may NOT be eligible if:** - You are not already scheduled for an endoscopic procedure - You are unable or unwilling to give informed consent - You have a condition that makes the fluid collection unsafe Talk to your doctor to see if this trial is right for you.