RecruitingNCT07030998

Wearable Technology and Machine Learning for Early Detection and Risk Assessment of Unacceptable Toxicities in a Paediatric Oncology Cohort

WEARABLES: Wearable Technology and Machine Learning for Early Detection and Risk Assessment of Unacceptable Toxicities in a Paediatric Oncology Cohort


Sponsor

Murdoch Childrens Research Institute

Enrollment

150 participants

Start Date

Oct 15, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Data collection study to establish a predictive model of infection observed during childhood cancer therapy using data captured by wearable technology.


Eligibility

Min Age: 5 YearsMax Age: 18 Years

Inclusion Criteria8

  • Paediatric, adolescent or young adult diagnosis of cancer AND receiving therapy placing them at risk of infection
  • Receiving cancer treatment at The Royal Children's Hospital
  • Patients aged 5-18 years at time of the eligibility screening
  • If aged < 16 years, parent or guardian able to provide consent
  • iPhone 8 or later (iOS must be up to date/updated at time of enrolment)
  • At least 10MB of iPhone storage for WEARABLES app and data collection.
  • Willing and able to wear a wearable device for a period of 4 weeks (during waking hours).
  • Consent to data being shared to the WEARABLES app (owned by the research team).

Exclusion Criteria4

  • <5 years of age.
  • <16 years of age without guardian or parent consent.
  • Aged 16-18 and unable to provide consent.
  • Participant did not consent to wearing Apple Watch for a period of 4 weeks.

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Interventions

DEVICEWearable Device

Wearable device to collect the following health metrics directly from participants for the duration of the study (4 weeks). Health metrics are collected every 15 minutes, except for the ECG which will be collected once per week. Data points: * ECG data (Once per week) * Exercise time * Body Temperature * Heart Rate * Irregular Heart Rhythm * Blood Oxygen Saturation * Respiratory Rate


Locations(1)

The Royal Children's Hospital

Parkville, Victoria, Australia

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NCT07030998


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