Infection Clinical Trials

1,473 recruitingLast updated: June 18, 2026

There are 1,473 actively recruiting infection clinical trials across 122 countries. Studies span Not Applicable, Phase 2, Phase 4, Phase 3, Phase 1, Early Phase 1. Top locations include New York, New York, United States, Houston, Texas, United States, Boston, Massachusetts, United States. Updated daily from ClinicalTrials.gov.


Infection Trials at a Glance

1,473 actively recruiting trials for infection are listed on ClinicalTrialsFinder across 6 cities in 122 countries. The largest study group is Not Applicable with 424 trials, with the heaviest enrollment activity in New York, Houston, and Boston. Lead sponsors running infection studies include National Institute of Allergy and Infectious Diseases (NIAID), Assistance Publique - Hôpitaux de Paris, and University Hospital, Strasbourg, France.

Treatments under study

About Infection Clinical Trials

Looking for clinical trials for Infection? There are currently 61 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Infection trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Infection clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 1,473 trials

Recruiting
Not Applicable

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S04)

Cervical CarcinomaHuman Papillomavirus Infection
National Cancer Institute (NCI)500 enrolled18 locationsNCT07281430
Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting

Navigating Pregnancy and Parenthood With Lyme Disease

Lyme DiseaseChronic Lyme DiseasePregnancy Complications+4 more
Children's National Research Institute30 enrolled1 locationNCT06397794
Recruiting
Phase 3

A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease

COVID-19 (SARS-CoV-2) infection
Pfizer2,330 enrolled246 locationsNCT06679140
Recruiting
Phase 3

A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised

COVID-19 Infection
Pfizer300 enrolled147 locationsNCT07013474
Recruiting

Pregnancy and Early Neurodevelopmental Outcomes Following In Utero Lyme Disease Exposure

Lyme DiseaseChronic Lyme DiseasePregnancy Complications+3 more
Children's National Research Institute40 enrolled1 locationNCT06026969
Recruiting
Phase 3

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

RSV Infection
Pfizer550 enrolled97 locationsNCT06866405
Recruiting

Combination vs. Monotherapy for Stenotrophomonas Maltophilia Infections

bloodstream infectionPneumonia, BacterialS Maltophilia Infections
Instituto de Investigación Sanitaria Gregorio Marañón790 enrolled1 locationNCT07593547
Recruiting
Phase 1Phase 2

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting

Evaluation of Patients With HAM/TSP

HTLV-I InfectionTropical Spastic Paraparesis
National Institute of Neurological Disorders and Stroke (NINDS)750 enrolled1 locationNCT00001778
Recruiting

Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

PneumoniaInfectionsImmune System Diseases+2 more
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT00006150
Recruiting
Phase 1

NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)

InfectionChronic Granulomatous Disease
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled1 locationNCT05189925
Recruiting
Phase 2

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

InfectionsAcute Respiratory Distress Syndrome
BioAegis Therapeutics Inc.600 enrolled70 locationsNCT05947955
Recruiting
Not Applicable

Preoperative Fasting and the Gut Microbiome Before Hip Replacement

Surgical wound infectionPostoperative ComplicationsGastrointestinal Microbiome+2 more
Charite University, Berlin, Germany130 enrolled1 locationNCT07651462
Recruiting

Modeling Host-Pathogen Interaction Using Lymphoid Organoids

Staphylococcal Infections
National Institute of Allergy and Infectious Diseases (NIAID)500 enrolled2 locationsNCT06479837
Recruiting
Phase 4

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Bacterial infection
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled10 locationsNCT06709521
Recruiting
Phase 1

Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.

InfluenzaAcute Respiratory Viral Infections
Valenta Pharm JSC36 enrolled1 locationNCT07645534
Recruiting

PK/PD Relationship of CAZ/AVI and FOS in the Treatment of Patients With Infections Due to CRE

Antimicrobial Resistance (AMR)Gram-negative Infections
IRCCS Azienda Ospedaliero-Universitaria di Bologna60 enrolled2 locationsNCT06717594
Recruiting

Epidemiology, Risk Factors, and Outcomes of Infections of Lower Limb MEGAprostheses

Lower Limb Megaprosthetis Infection
IRCCS Azienda Ospedaliero-Universitaria di Bologna200 enrolled1 locationNCT07544212
Recruiting
Phase 2

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Gram-Negative Bacterial Infections
Pfizer48 enrolled24 locationsNCT05639647