RecruitingPhase 1NCT07031713

Safety, Efficacy and Cellular Metabolic Dynamics of ct1192 in Patients With Moderate to Severe Refractory SLE

A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Dynamics of Universal CD19 / 20 Car-t Cell Injection in Moderate to Severe Refractory Systemic Lupus Erythematosus


Sponsor

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Enrollment

12 participants

Start Date

Jul 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A clinical study to explore the safety, efficacy and cell metabolic kinetics of universal CD19/20 car-t cell injection in moderate to severe refractory systemic lupus erythematosus. This study is a single arm, open, exploratory dose increasing clinical study, which aims to evaluate the safety, efficacy and cell metabolic dynamics of ct1192 cells in patients with SLE.


Eligibility

Min Age: 18 YearsMax Age: 60 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called CAR-T Therapy for people with systemic lupus erythematosus (sle). The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALCAR-T Therapy

CT1192 cells infusion


Locations(1)

Wuhan Union Hospita

Wuhan, Hubei, China

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NCT07031713


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