An Observational Study of Molecular profIling of Advanced and aggRessive ENdometrial Cancer and 1-st Line Treatment Approaches in Russian Federation

This observational study is collecting detailed molecular and genetic information from tumor samples of women in Russia with advanced or aggressive uterine cancer (endometrial cancer). The goal is to better understand the biology of these cancers and how they respond to first-line treatment, which may help guide future treatment decisions. **You may be eligible if...** - You are a woman 18 or older - You have been newly diagnosed with advanced-stage (III or IV) endometrial cancer, confirmed within the past 4 months - Your cancer is a high-grade or aggressive type (such as serous, clear cell, or dedifferentiated carcinoma) - You are willing to allow your archived tumor tissue sample to be tested - You have signed the informed consent form **You may NOT be eligible if...** - Your diagnosis was made more than 4 months ago - You have a low-grade (Grade 1 or 2) endometrioid cancer - You are unwilling to allow tissue testing - You are unable to provide informed consent Talk to your doctor to see if this trial is right for you.