MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003)

This study is testing an experimental drug called MK-4646, given in multiple doses to people living with HIV-1 who are not currently on antiretroviral (HIV) treatment. The goal is to understand the drug's safety, how the body handles it over time, and how it affects HIV levels in the blood. **You may be eligible if...** - You have HIV-1 but are otherwise in good general health - You have never received antiretroviral therapy, OR you have not taken any antiretroviral drugs in the past 60 days - You are willing to temporarily stop any antiretroviral therapy during the study period - If you can produce sperm, you are willing to use contraception - If assigned female sex at birth, you are not pregnant or breastfeeding **You may NOT be eligible if...** - You are currently on antiretroviral therapy that you are not able or willing to pause - You are pregnant or breastfeeding - You have significant health conditions beyond HIV that would affect safety - Your CD4 cell count or viral load is outside the acceptable range for the study Talk to your doctor to see if this trial is right for you.