Cardiovascular-Kidney-Metabolic Syndrome in Shanghai Zicitizens

This is a follow-up observational study in Shanghai, China, that tracks residents enrolled in the STONE cohort since 2016–2017 to study cardiovascular-kidney-metabolic (CKM) syndrome — a cluster of conditions including heart disease, kidney disease, diabetes, and obesity that often occur together. The study re-examines these participants years later to understand how these conditions develop and interact over time. **You may be eligible if...** - You are one of the 4,094 residents originally enrolled in the STONE cohort between 2016 and 2017 - You completed the baseline questionnaire, physical exam, and clinical tests at that time - You are willing to participate in this follow-up study and can provide consent **You may NOT be eligible if...** - You have moved away from your original community for more than two years - You are no longer reachable through your original contact information - You are no longer alive or able to participate Talk to your doctor to see if this trial is right for you.