RecruitingNCT07043491

Comparison of Endoscopy and Esophagram for the Routine Evaluation of Anastomosis After McKeown Esophagectomy


Sponsor

Sun Yat-sen University

Enrollment

2 participants

Start Date

Nov 4, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This retrospective cohort study reviewed patients who underwent McKeown esophagectomy. All patients routinely underwent either endoscopy or esophagram for the evaluation of anastomosis on postoperative day 7. The initiation of oral intake depended on the status of anastomosis according to the assessment result of endoscopy or esophagram. All patients were followed up for six months after the assessment of anastomosis.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This observational study is comparing two methods used to check the healing of a surgical connection (anastomosis) after esophageal cancer surgery (McKeown esophagectomy): endoscopy (a camera inserted down the throat) versus an esophagram (an X-ray taken after swallowing contrast dye). The goal is to determine which method is more reliable and practical for routine post-surgery monitoring. **You may be eligible if...** - You have already undergone either endoscopy or an esophagram as part of your routine post-surgery care after McKeown esophagectomy **You may NOT be eligible if...** - Your original tumor was a benign (non-cancerous) lesion of the esophagus or stomach junction - Your medical records are incomplete Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTEndoscopy

We first observed the residual esophagus to evaluate the mucosal color. We then reached the top of the anastomosis to obtain a full view of the anastomosis to exclude obvious leakage around that site. We next conducted a more detailed endoscopic examination at a close focal distance, circumferentially around the anastomosis. During this process, we utilized saline solution to meticulously remove white fibrin coverings and bloodstains to the greatest extent possible to ensure a thorough evaluation of anastomotic integrity. Finally, we inspected the staple line of the tubularized stomach to exclude gastric fistula and assessed the perfusion of the gastric graft. Endoscopic findings were assessed by an additional endoscopist and 3 esophageal surgeons during the examination, as well as by reviewing captured images or videos after endoscopy.


Locations(1)

Sun Yat-sen University Cancer Center

Guangzhou, Guangdong, China

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NCT07043491


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