RecruitingNCT07050823

Mitigating Chronic Respiratory Disease Through the Lens of Multi-Morbidity

Case-Finding for Chronic Respiratory Diseases in People Living With Other Long-Term Conditions


Sponsor

University College, London

Enrollment

859 participants

Start Date

Jul 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The investigators aim to make it easier to find people with undiagnosed long-term lung health problems (such as asthma, and chronic obstructive pulmonary disease, COPD, collectively called 'Chronic Respiratory Diseases', CRDs) living in Brasil. Because people with undiagnosed CRDs often have other medical problems too, such as heart problems, high blood pressure and diabetes (collectively called 'Long Term Conditions', LTC), the investigators will look for undiagnosed CRD in people with LTC when they are attending appointments at local health centres in the cities of Sao Carlos and Sao Paulo. To look for undiagnosed CRDs the investigators will use two questionnaire-based methods called 'COLA' and 'SBQ'. These are quick and simple to do. All participants will also have tests of their lung function completed including spirometry and Fractional Exhaled Nitric Oxide so that the investigators can make a definite diagnosis of CRDs. When the study is complete, the investigators will examine how well the COLA and SBQ questionnaires perform in identifying people with a definite diagnosis of CRD. In total, the investigators aim to recruit 859 people.


Eligibility

Min Age: 30 Years

Plain Language Summary

Simplified for easier understanding

This study looks at whether people in Brazil who already have chronic conditions like heart disease, diabetes, or high blood pressure are also unknowingly developing chronic lung disease (such as COPD or asthma). Researchers want to find lung problems early, before symptoms become serious. **You may be eligible if:** - You attend a primary healthcare service in Brazil - You have been diagnosed with one or more existing long-term (non-respiratory) conditions such as cardiovascular disease, diabetes, or high blood pressure **You may NOT be eligible if:** - You have been clinically unstable in the past month (e.g., hospitalized or had worsening symptoms requiring emergency care) - You are currently pregnant - You have active or recently treated pulmonary tuberculosis - You have an active respiratory infection right now - You have significant cognitive impairment that prevents you from understanding the questionnaire - You have a medical reason not to do a breathing test (spirometry) - You decline to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(2)

Multiple primary care sites

São Carlos, São Paulo, Brazil

Multiple primary care sites

São Paulo, São Paulo, Brazil

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NCT07050823


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