Effect of Vitamin D on Cardiovascular Metabolic Risk in Overweight/Obesity Adolescents in China
The Improvement Effect of Vitamin D on the Cardiovascular Health of Overweight/Obesity Adolescents in China
Anhui Medical University
130 participants
Sep 15, 2025
INTERVENTIONAL
Conditions
Summary
The goal of this randomized controlled clinical trial is to investigate the effects of vitamin D3 supplementation on cardiometabolic risk in Chinese adolescents with overweight/obesity and vitamin D deficiency. The main question it aims to answer whether vitamin D3 supplementation can improve cardiovascular metabolic health. Participants in the intervention group will receive vitamin D3. The control group will receive vitamin D placebo. Researchers will compare the change in cardiometabolic risk from baseline to post-intervention at 12 weeks between the intervention and control groups.
Eligibility
Inclusion Criteria3
- Students whose caregivers signed informed consents;
- Students with serum 25(OH)D concentration of 12-20 ng/mL;
- Students with overweight or obesity.
Exclusion Criteria3
- Students with any disease that affects vitamin D metabolism (e.g., functional/organic brain disease, severe infectious disease, chronic gastrointestinal disease, hepatic or renal insufficiency, etc.);
- Students with known chronic disease (e.g., cardiovascular disease); use of vitamin D supplements in the past 3 months;
- Students with allergies to vitamin D or soybean oil ingredients.
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Interventions
2000 IU per day for 6 weeks (two capsules of 800 IU plus one capsule of 400 IU), followed by 800 IU (one capsule of 800 IU) per day for 6 weeks.
Three capsules for 6 weeks, followed by one capsule for 6 weeks.
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07053657