RecruitingPhase 1NCT07053670

A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 )

A Clinical Study to Investigate the Safety, Efficacy, and Cellular Metabolism of CT1190B CAR-T Cell Therapy, in Patients With Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma


Sponsor

Tongji Hospital

Enrollment

27 participants

Start Date

Jul 9, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

A Clinical Study to Investigate the Safety, Efficacy, and Cellular Metabolism of CT1190B CAR-T Cell therapy, in Patients with Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This trial tests a new experimental drug called CT1190B in people with blood cancers — specifically lymphomas and leukemias — that have returned or stopped responding to previous treatments. The study aims to find the right dose and assess how safe and effective the drug is. **You may be eligible if...** - You have a relapsed or refractory blood cancer (lymphoma or leukemia) that has not responded to standard treatments - You have tried at least one prior treatment - Your overall health and organ function are adequate to receive the experimental drug - You are 18 or older **You may NOT be eligible if...** - You have active brain involvement by your cancer - You have a serious uncontrolled infection - You have significant heart, liver, or kidney disease - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCAR T cells

chimeric antigen receptor T cells


Locations(1)

Tongji Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

Wuhang, Hubei, China

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NCT07053670


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