Tumor-Lymph Node Mapping
FEASIBILITY AND SAFETY OF INDOCYANINE GREEN (ICG) GUIDED SENTINEL LYMPH NODE MAPPING FOR PEDIATRIC SOLID TUMORS - T-LyM (Tumor-Lymph Node Mapping)
University of Rochester
10 participants
Apr 13, 2026
OBSERVATIONAL
Conditions
Summary
The purpose of this study is to assess the feasibility and safety of ICG-guided intraoperative lymphography for detecting sentinel lymph nodes (SLN) in pediatric patients with solid tumors who require retroperitoneal lymph node dissection/sampling. This trial is a single-site cross-sectional study. The injection of ICG directly into lymphatics draining the primary tumor will take place at the time of operation after the patient is under anesthesia.
Eligibility
Inclusion Criteria3
- Any pediatric patient (under the age of 18 years) being treated at the University of Rochester Medical Center, Department of Surgery.
- Diagnosed with pediatric solid tumor
- Scheduled to undergo lymph node sampling as part of their clinical management.
Exclusion Criteria5
- Subjects with a history of iodide allergies.
- Inability or unwillingness of research participant or parent/legal guardian to give written informed consent.
- Currently pregnant.
- Infants under 650 grams.
- Patients with extensive prior surgery at the primary site or nodal basin expected to affect the lymphatic drainage.
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Interventions
Lymphatic mapping
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07054944