RecruitingNot ApplicableNCT07058727

Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain

The Effect of Different Hemostatic Agents Used in Partial Pulpotomy on Pulp Survival and Postoperative Pain: A Randomized Clinical Trial


Sponsor

Cukurova University

Enrollment

75 participants

Start Date

May 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized clinical trial evaluates the efficacy of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and cold saline as hemostatic agents in partial pulpotomy. The study compares postoperative pain (via VAS scores) and pulp survival (via clinical/radiographic evaluation) at 1, 3, 7 days, 6 months, and 12 months


Eligibility

Min Age: 15 YearsMax Age: 55 Years

Inclusion Criteria3

  • Permanent teeth with carious pulp exposure (no spontaneous pain).
  • Positive vitality test (Endo-Ice).
  • No periapical radiolucency.

Exclusion Criteria3

  • Systemic diseases affecting healing.
  • Pregnancy.
  • Non-vital pulp/necrosis

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Interventions

DRUGSodium Hypochlorite 2,5%

2.5% NaOCl applied for 1 min to exposed pulp for hemostasis, followed by standard pulp capping

DRUGChlorhexidine

2% CHX applied for 1 min to achieve hemostasis, with identical subsequent steps to NaOCl group

DRUGCold Saline

Hemostasis via 4°C saline (1 Min), then standardized pulp capping


Locations(1)

Çukurova Üniversitesi Diş Hekimliği Fakültesi

Adana, Sarıçam, Turkey (Türkiye)

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NCT07058727


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