RecruitingNot ApplicableNCT07058870

Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment: A Feasibility Study

Unravelling The Optimisation And Consolidation Of Motor Skills In People With Multiple Sclerosis With Mild to Moderate Gait Impairment Via High Intensity Task Oriented Circuit Training: A Feasibility Study


Sponsor

University Hospital of Ferrara

Enrollment

18 participants

Start Date

Oct 15, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this feasibility study is to test the safety and effectiveness of an high-intensity task oriented circuit training program, followed by three months of telerehabilitation in people with mild to moderate Multiple Sclerosis (MS). The main questions it aims to answer are: * Can high-intensity task oriented circuit training improve gait and balance functional capacity? * Can telerehabilitation mantain the benefits in gait and balance gained via circuit training for a six month period? Participants will: * Complete 10 session ( one hour each, three times a week) of high-intensity task oriented circuit training administered in a hospital setting. The training will target key motor skills such as walking, stepping, supine to stand transitions and general mobility. * Engage in 3 months of asynchronous telerehabilitation (without physiotherapist supervision)


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria3

  • Diagnosis of primary or secondary progressive multiple sclerosis according to the McDonald criteria.
  • Mini-Mental State Examination (MMSE) score \> 24.
  • Expanded Disability Status Scale (EDSS) score ≤ 6.

Exclusion Criteria4

  • Presence of other psychiatric or neurological disorders.
  • Cardiopulmonary, renal, or liver diseases.
  • Pregnancy.
  • Modifications in drug treatment within the last 3 months.

Interventions

BEHAVIORALHigh Intensity Task Oriented Circuit Training + Telerehabilitation

Participants will receive 10 sessions of high-intensity, task-oriented circuit training, three times a week. Each session will last 60 minutes, with minutes of active training. Each session will include three rounds, each lasting 55 minutes. During each round, participants will rotate between stations working for four minutes at each station, followed by three minutes of rest. The stations will focus on key motor skills, including supine to stand transitions, walking speed and functional capacity, walking adaptability and stepping. After in-hospital treatment participants will receive 36 sessions of asynchronous telerehabilitation, three times a week for 12 weeks. This intervention will be supported by low-cost, off-the-shelf technology for treatment delivery and monitoring.


Locations(1)

Ferrara University Hospital

Ferrara, FE, Italy

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NCT07058870


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