Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty
Ultrasound-guided Rectus Abdominis Muscle Sheath Block in Outpatient Umbilical Hernioplasties: a Comparative Analysis of the Use of Clonidine as an Adjuvant - Prospective Randomized Clinical Trial
Universidade Federal do Rio de Janeiro
62 participants
Jan 7, 2025
INTERVENTIONAL
Conditions
Summary
This clinical trial aims to evaluate the effectiveness of an ultrasound-guided nerve block technique as the sole anesthetic method for patients undergoing outpatient umbilical hernia surgery. The procedure, called rectus sheath block (RSB), involves injecting local anesthetic near the abdominal muscles to reduce pain during and after surgery. The study will compare two groups of adult patients: one receiving the nerve block with a medication called clonidine added to the anesthetic solution, and the other receiving the same block without clonidine. Clonidine may help improve pain control and reduce the need for additional pain medications. By analyzing pain scores, recovery quality, and potential side effects, the study seeks to determine whether the use of clonidine in this context is safe, cost-effective, and beneficial for patient recovery. Participants will answer questionnaires about their pain and recovery during the first 48 hours after surgery.
Eligibility
Inclusion Criteria5
- Adults aged 18 to 65 years;
- Both male and female participants;
- ASA physical status I or II (American Society of Anesthesiologists classification);
- Scheduled for elective ambulatory umbilical hernia repair;
- Hernial defect size ≤ 4 cm (small to medium).
Exclusion Criteria6
- Refusal or inability to provide written informed consent;
- Cognitive or psychiatric disorders that impair comprehension or adherence to the study protocol;
- Known allergy or hypersensitivity to local anesthetics, clonidine, opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), or other analgesics;
- Participation in another clinical trial within the previous 30 days;
- Missing data or loss to follow-up during postoperative assessments;
- Contraindications to regional anesthesia or known coagulopathy.
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Interventions
Participants in this arm will receive bilateral ultrasound-guided rectus sheath block (RSB) with a solution containing 8 mL of lidocaine 2% + 8 mL of ropivacaine 1%, diluted in 0.9% saline to a total volume of 20 mL, each side, without the addition of clonidine.
Participants in this arm will receive bilateral ultrasound-guided rectus sheath block (RSB) with a solution containing 8 mL of lidocaine 2% + 8 mL of ropivacaine 1% + clonidine 75 mcg, diluted in 0.9% saline to a total volume of 20 mL, each side, without the addition of clonidine.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07062497