RecruitingNot ApplicableNCT07063563

Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in COPD-patients

Effect of Rehabilitation at Moderate Altitude on Airway Resistance Measured With Forced Oscillation Technique in Patients With COPD


Sponsor

Eastern Switzerland University of Applied Sciences

Enrollment

52 participants

Start Date

Jul 23, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Airway resistance will be measured using the forced oscillation technique (FOT). The parameters Rrs, Xrs, and ∆Xrs will be compared before and after a pulmonary rehabilitation cycle at moderate altitude. Additionally, the differences between low and moderate altitude will also be examined.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study looks at how a rehabilitation program at moderate altitude (about 1,500–2,000 meters above sea level) affects airway resistance and breathing in people with COPD (chronic obstructive pulmonary disease — a long-term lung condition causing breathing difficulties). **You may be eligible if...** - You are 18 years or older - Your COPD has been stable for more than 3 weeks (no recent flare-ups) - Your resting blood oxygen level is at least 88% on a pulse oximeter - Your oxygen levels drop significantly during a 6-minute walk test - You are willing and able to provide informed consent **You may NOT be eligible if...** - Your oxygen levels are dangerously low at rest (below 88%) - You are on continuous oxygen therapy - You have an unstable condition requiring medication changes or intensive care - You have a condition that prevents you from walking or cycling (e.g., serious orthopedic or neurological problems) - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERambiant air

Standard ambiant air will be breathed during endurance training. ambiant air

OTHEROxygen

SSOT and sham air (5l/min) will be applied with the oxygen concentrator EverFloTM via nasal cannula during training

OTHERambiant air

Standard ambiant air will be breathed during endurance training. ambiant air


Locations(2)

National center for cardiology and internal medicine

Bishkek, Kyrgyzstan, Kyrgyzstan

Eastern Switzerland University of Applied Sciences

Sankt Gallen, Canton of St. Gallen, Switzerland

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NCT07063563


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