RecruitingNot ApplicableNCT07065604

Tubeless VATS for Mediastinal Neoplasm

A Randomized Controlled Trial of Non-intubated Versus Intubated VATS for Mediastinal Neoplasm

Sponsor

Shuben Li

Enrollment

132 participants

Start Date

Mar 26, 2025

Study Type

INTERVENTIONAL

Conditions

Mediastinal Neoplasm VATS Tubeless Non-intubated Anesthesia

Summary

In recent year, non-intubated anesthesia had emerged as an available and promising alternative for thoracic procedure. However, its safety and feasibility in video-assisted thoracoscopic surgery (VATS) for mediastinal neoplasm remain controversial. This randomized controlled trial is designed to evaluate the impact of the non-intubated approach on surgical and perioperative outcomes in patients undergoing mediastinal neoplasm resection.

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria5

Mediastinal neoplasm was diagnosed by chest enhanced CT
The patients with age ≥ 18 and ≤ 80 years old
The patients whose tumor diameter was \<6 cm
ASA grade: I-III
The patients should understand the research and sign the informed consent

Exclusion Criteria3

Imaging examinations revealed that the tumor had invaded adjacent organs, with evidence of pleural or pericardial dissemination, as well as lymphatic and/or hematogenous metastases
Patients with a confirmed history of congestive heart failure, poorly controlled angina despite medical therapy, electrocardiogram-confirmed myocardial infarction with transmural involvement, uncontrolled hypertension, clinically significant valvular heart disease, or high-risk arrhythmias not adequately managed
Patients with concurrent active malignancies

Print for Your Doctor

Interested in this trial?

Get notified about updates and connect with the research team.