ColoSense Post-Approval Study

This study is collecting real-world data on how well the ColoSense stool DNA test (a non-invasive at-home colorectal cancer screening test) performs in a broad population — comparing results to colonoscopy findings to confirm the test's accuracy after its approval. **You may be eligible if...** - You are 45 or older (those 18–44 may enroll but are not part of the primary analysis) - You are willing and able to provide a stool sample and then undergo a colonoscopy afterward **You may NOT be eligible if...** - You have a history of colorectal cancer or precancerous polyps - You have had a colonoscopy in the past 9 years - You have inflammatory bowel disease (IBD), Lynch syndrome, or familial adenomatous polyposis (FAP) - You have recently had a positive non-invasive cancer screening test - You have had active rectal bleeding in the past 30 days Talk to your doctor to see if this trial is right for you.