RecruitingNot ApplicableNCT07070778

Arterial Stiffness in Individuals With Breast Cancer

The Effect of Upper Extremity Aerobic Exercise Training on Arterial Stiffness in Individuals With Breast Cancer

Sponsor

Hacettepe University

Enrollment

18 participants

Start Date

Jul 8, 2025

Study Type

INTERVENTIONAL

Conditions

Breast Cancer Arterial Stiffness Aerobic Exercise

Summary

The aim of this study was to evaluate vascular toxicity induced by anthracyclines and other anticancer drugs and to measure arterial stiffness in women with breast cancer and, in addition, to evaluate the acute and chronic arterial stiffness responses of upper extremity aerobic exercise training.

Eligibility

Sex: FEMALEMin Age: 40 YearsMax Age: 69 Years

Inclusion Criteria8

To be between the ages of 40-69,
Baseline left ventricular ejection fraction (LVEF) \>50%,
Absence of coronary artery disease and haemodynamically significant valvular heart disease,
Absence of carotid atherosclerotic plaques,
Volunteering to participate in the research,
At least 15 months after breast cancer surgery,
No problems in reading and/or understanding the scales and being able to co-operate with the tests.
Physically inactive (60 minutes of structured exercise per week \<).

Exclusion Criteria7

Presence of active infection,
Presence of bilateral breast cancer,
History of surgical, neurological or orthopaedic problems that may affect upper extremity functionality other than breast cancer surgery,
Having a neurological disease or other clinical diagnosis that may affect cognitive status,
Left ventricular dysfunction and severe liver and kidney dysfunction before starting chemotherapy
Musculoskeletal and neurological disease that may affect exercise performance, symptomatic heart disease, previous lung surgery and malignant disease.
Presence of unstable hypertension or diabetes mellitus.