RecruitingNot ApplicableNCT07075276

Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Temporomandibular Disc Displacement

Injection of Liquid Phase Concentrated Growth Factor Versus Conventional Arthrocentesis in Management of Temporomandibular Disc Displacement: A Randomized Controlled Clinical Trial

Sponsor

Horus University

Enrollment

32 participants

Start Date

Oct 1, 2025

Study Type

INTERVENTIONAL

Conditions

Temporomandibular Disorders (TMD)Internal Derangement of the Tempromandibular Joint Anterior Disc Displacement

Summary

This study aims to rigorously assess the effectiveness of LPCGF in the management of internal disc displacement in patients with TMD through a randomized clinical trial. By comparing LPCGF therapy with conventional arthrocentesis, this research looks to provide robust evidence on the efficacy, safety, and potential role of (LPCGF) as an alternative therapeutic choice for IDD.

Eligibility

Min Age: 18 YearsMax Age: 45 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a procedure called Conventional arthrocentesis and a procedure called Liquid Phase Concentrated Growth Factor for people with anterior disc displacement, internal derangement of the tempromandibular joint, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 45 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDURELiquid Phase Concentrated Growth Factor

16 patients with anterior disc displacement with or without reduction randomly allocated to be treated with injection of liquid phase concentrated growth factor

PROCEDUREConventional arthrocentesis

16 patients with anterior disc displacement with or without reduction randomly allocated to be treated with conventional arthrocentesis

Locations(1)

Faculty of Dentistry- Horus University in Egypt

Damietta, New Damietta, Egypt

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NCT07075276

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