Comparison Between the Efficacy of Albumin Versus Hyaluronic Acid Scaffold in Combination With Concentrated Growth Factors as an Adjunct to Non-surgical Treatment of Periodontitis
Comparison Between the Efficacy of Albumin Versus Hyaluronic Acid Scaffold in Combination With Concentrated Growth Factors as an Adjunct to Non-surgical Treatment of Periodontitis (Randomized Controlled Clinical Trial)
husain abduljalil alam
30 participants
Jul 7, 2025
INTERVENTIONAL
Conditions
Summary
The primary objective is to clinically evaluate the efficacy of albumin versus hyaluronic acid scaffolds in combination with concentrated growth factors in the non- surgical treatment of stage II/III periodontitis. The secondary objective is to evaluate the duration and concentration of different growth factors release in the gingival crevicular fluid.
Eligibility
Inclusion Criteria2
- Patients aging from 25-45 years
- Patients with stage II /III periodontitis
Exclusion Criteria6
- Any systemic condition that may impact the study (21)
- Poor oral hygiene
- Pregnant and breastfeeding women
- Smoking patients.
- Patients received periodontal treatment in the last 6 months
- Unable to comply with study protocol
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Interventions
patients will receive hyaluronic acid mixed with concentrated growth factors injected into the periodontal pocket after mechanical debridement
patients will receive Albumin gel mixed with concentrated growth factors injected into the periodontal pocket after mechanical debridement
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07081230