Periodontitis Clinical Trials

8 recruiting

Frequently Asked Questions

Common questions about Periodontitis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Effects of Periodontal Treatment Associated With Antimicrobial Photodynamic Therapy on Halitosis in Patients With Diabetes Mellitus

Type 2 DiabetesHalitosisPeriodontitis
University of Sao Paulo32 enrolled1 locationNCT07463859
Recruiting
Not Applicable

Para-Probiotic Oral Care in Periodontal Patients With Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)Periodontitis
University of Pavia40 enrolled1 locationNCT07069166
Recruiting
Early Phase 1

Effect of Arestin-Enhanced SRP on Periodontal and Glycemic Outcomes in Diabetics

Periodontitis, Diabetes Mellitus Type 2
Case Western Reserve University42 enrolled1 locationNCT07298057
Recruiting
Not Applicable

Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain

Asymptomatic Apical Periodontitis
Fatima Memorial Hospital60 enrolled1 locationNCT07256691
Recruiting
Not Applicable

Non-surgical Periodontal Therapy and Kidney Outcomes in Type 2 Diabetes Mellitus

Type 2 Diabetes Mellitus MeSH:D003924Periodontitis MeSH:D010518Diabetic Nephropathies MeSH:D003928
Dow University of Health Sciences46 enrolled1 locationNCT07256613
Recruiting
Not Applicable

Regular Use of aPDT in the Management and Prevention of Periodontitis Symptoms in Diabetic Patients

Diabetes Mellitus, Type 2Periodontal DiseasesPeriodontitis+1 more
Wellbeing Services County of Pirkanmaa150 enrolled1 locationNCT06486012
Recruiting

The Role of Toll-like Receptor-4 in Periodontitis Patients With End-stage Renal Disease in a Sample of Egyptian Population

End Stage Renal DiseasePeriodontitis
Ain Shams University100 enrolled1 locationNCT06755372
Recruiting
Not Applicable

Effect of Periodontal Treatment on Metabolic Control in Patients with Type-2 Diabetes Mellitus Treated in the Cardiovascular Healt Program

Diabetes Mellitus, Type 2Periodontitis Chronic Generalized ModeratePeriodontitis+1 more
University of Chile80 enrolled1 locationNCT06895980
Recruiting

Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study

Alzheimer DiseasePeriodontitis
Centre Hospitalier Universitaire de Nice94 enrolled1 locationNCT05077618
Recruiting
Not Applicable

Effect of Endodontic Treatment on Inflammatory Markers, Disease Activity and Periapical Healing in Rheumatoid Arthritis Patients With Apical Periodontitis : A Prospective Interventional Study

Rheumatoid Arthritis AND Apical Periodontitis
Postgraduate Institute of Dental Sciences Rohtak76 enrolled1 locationNCT06433232
Recruiting
Not Applicable

Impact of Periodontal Therapy on Mental Health Parameters

DepressionPeriodontitis
Universidad Complutense de Madrid40 enrolled2 locationsNCT06036472
Recruiting

Relationship Between Major Depression and Periodontal Diseases

Major Depressive DisorderPeriodontitis
Universidad Complutense de Madrid122 enrolled2 locationsNCT05950009