RecruitingNot ApplicableNCT07082894

Effect of Preoperative Oral Magnesium on Emergence Agitation

The Effect of Preoperative Oral Magnesium on Emergence Agitation in Children Undergoing Adenotonsillectomy: A Double Blind Randomized Placebo Controlled Study


Sponsor

Tanta University

Enrollment

120 participants

Start Date

Jul 25, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This prospective randomized controlled study will be conducted to evaluate the effects of preoperative oral magnesium on the incidence and severity of emergence agitation in children undergoing adenotonsillectomy using sevoflurane anesthesia.


Eligibility

Min Age: 4 YearsMax Age: 7 Years

Inclusion Criteria4

  • Both gender
  • to 7 years age
  • American Society of Anesthesiologists (ASA) Physical Status I or II
  • Scheduled for adenotonsillectomy surgery under sevoflurane anesthesia

Exclusion Criteria6

  • Parents declined to participate in the trial
  • Children with behavioral changes; neurological or psychiatric diseases
  • Physical or developmental delay
  • Sedative or anticonvulsant medication
  • Pre-existing renal or cardiovascular disease, bone disease, or gastrointestinal disorders
  • Allergy to magnesium

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Interventions

DRUGMagnesium

preoperative oral magnesium dose of 120 mg at one hour before surgery will be given.

OTHERPlacebo control

preoperative oral lemon juice at one hour before surgery will be given.


Locations(1)

Tanta University

Tanta, Gharbia Governorate, Egypt

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NCT07082894


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