RecruitingNot ApplicableNCT07084597

Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D

Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male

Sponsor

Bangladesh Medical University

Enrollment

15 participants

Start Date

Jul 1, 2025

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done. Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV

Eligibility

Sex: MALEMin Age: 51 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether vitamin D3 supplements can help improve the function of nerves that control the heart in men with Parkinson's disease who also have low vitamin D levels. Poor nerve control of the heart can increase the risk of falls and other complications in Parkinson's. **You may be eligible if...** - You are a male between 51 and 70 years old - You have been diagnosed with Parkinson's disease by a neurologist, with mild to moderate disability - Your vitamin D levels are low (deficient or insufficient) - You are currently taking levodopa medication for Parkinson's - Your BMI is in the normal range (18.5 to 24.9) **You may NOT be eligible if...** - You have a history of alcohol or drug abuse - You take antioxidant supplements, cholesterol-lowering drugs, blood pressure medications, anti-arrhythmia drugs, or sedatives - You have severe heart or neurological conditions beyond Parkinson's - You have kidney problems or other serious illnesses Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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