RecruitingPhase 2Phase 3NCT07084662

Xinlikang Capsule for Chemotherapy-induced Fatigue and Immune Disorders in Diffuse Large B Lymphoma

A Prospective, Multicenter, Randomized, Double-blind, Placebo-controlled Clinical Trial of Xinlikang Capsule in the Treatment of Chemotherapy-induced Fatigue and Immune Disorders in Patients With Diffuse Large B Lymphoma


Sponsor

Sun Yat-sen University

Enrollment

80 participants

Start Date

Sep 11, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To evaluate the efficacy and safety of Xinlikang capsule in the treatment of cancer-related fatigue (CRF) and peripheral blood lymphocytes in patients with diffuse large B-cell lymphoma (DLBCL) who achieved complete remission (CR) after all courses of chemotherapy-containing regimens


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether a traditional Chinese herbal medicine capsule called Xinlikang can reduce fatigue and immune problems in people who have completed treatment for a type of blood cancer called diffuse large B-cell lymphoma (DLBCL) and are in complete remission. **You may be eligible if...** - You are 18 or older - You have been diagnosed with diffuse large B-cell lymphoma (DLBCL) - You have completed your full course of chemotherapy and immunotherapy and your cancer is in complete remission, confirmed by PET/CT scan - You finished chemotherapy 30 to 90 days ago - You are experiencing moderate to severe fatigue (score of 4 or more on the BFI scale) - You do not plan to start other cancer treatments in the next 3 months **You may NOT be eligible if...** - Your cancer has not achieved complete remission - You are currently using other Chinese herbal treatments or immunosuppressive agents - You have major surgery planned in the next 3 months - Your liver or kidney function is significantly impaired Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGXinlikang capsules

Xinlikang capsules after meals, 5 capsules each time, 3 times a day for 12 weeks

DRUGmimic capsules

mimic capsules, 5 capsules each time after meals, 3 times a day for 12 weeks.


Locations(1)

Sun Yat-sen Universitiy Cancer Center, Sun Yat-Sen University

Guangzhou, Guangdong, China

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NCT07084662


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