RecruitingNot ApplicableNCT07086144

Efficacy of a Myocardial Panel in the Management and Treatment of Pediatric Myocarditis

Efficacy of a Myocardial Panel (Virological, Bacterial and Autoimmune) in the Management and Treatment of Pediatric Myocarditis Complicated With Arrhythmias or Ventricular Dysfunction


Sponsor

Azienda Ospedaliero, Universitaria Ospedali Riuniti

Enrollment

30 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this observational study is to determine the efficacy a of combined management and treatment driven by the systematic determination of viral genome, bacterial serology, and markers of inflammation in pediatric patients (\< 18 years old) diagnosed with myocarditis complicated by arrhythmias (supraventricular and ventricular tachycardias and heart block) or ventricular dysfunction (left ventricular ejection fraction \< 50% or right ventricular fractional area change \< 35%). The main question it aims to answer is: Does this panel help resolve arrhythmias or myocardial dysfunction due to myocarditis during hospitalisation and follow-up? Researchers will compare patients managed and treated in 2024 without applying the myocarditis panel with those enrolled in 2025 who received the panel. Arrhythmias and myocardial dysfunction will be managed in accordance with recent guidelines. Antiviral, antibiotic or immunosuppressive therapies will be implemented in addition to standard therapy when required by the panel.


Eligibility

Max Age: 18 Years

Inclusion Criteria1

  • All the consecutive pediatric patients (< 18 years old) presenting with myocarditis complicated by arrhythmias or myocardial dysfunction

Exclusion Criteria2

  • Refused consent to be included in the study given by parents or legal tutors
  • Uncomplicated myocarditis presenting without arrhythmias or myocardial dysfunction

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTDetermination of viral genome, bacterial serology, and markers of inflammation in pediatrics diagnosed with myocarditis

N=15 patients from 2025, in which management and treatment of arrhythmias and or myocardial dysfunction were driven by the panel


Locations(1)

Francesco Bianco

Ancona, The Marches, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07086144


Related Trials