RecruitingNCT07087145

Feasibility of HPV Testing With Mail-delivered Sample Collection Kits

Persistent Oral HPV Among Diverse PLWH: A Pilot Study to Evaluate the Feasibility and Acceptability of Testing for Oral HPV DNA Infection With Mail-delivered Sample Collection Kits

Sponsor

University of California, San Francisco

Enrollment

135 participants

Start Date

Nov 17, 2024

Study Type

OBSERVATIONAL

Conditions

HIV Infections HPV-Related Malignancy HPV Infection

Summary

People living with human immunodeficiency virus (PLWH) have an estimated 1.6-6.0 times increased risk of developing oropharyngeal cancer (OPC) compared with individuals in the general population. 70% of OPCs are caused by human papillomavirus (HPV), and PLWH also have an increased prevalence of oral HPV infection. Disparities by race/ethnicity also include a later stage of diagnosis and less frequent cancer-directed treatment for members of ethnic minority groups. There is little known regarding the racial/ethnic differences in oral HPV infection, persistence of oral HPV infection, or progression of oral HPV infection to OPC among PLWH. This is an observational, prospective cohort study to investigate the feasibility of alternative sample collection methods for HPV testing among PLWH.

Eligibility

Min Age: 35 Years

Plain Language Summary

Simplified for easier understanding

This study is testing whether mail-delivered HPV self-testing kits are a practical and acceptable way for sexual minority men and trans-women living with HIV to screen for HPV (human papillomavirus) infections. The goal is to find easier, more accessible ways for this community to get tested. **You may be eligible if...** - You are over 35 years old - You identify as a man who has sex with men, or as a trans-woman - You are living with HIV - You can receive and return packages by US mail and FedEx - You are able to visit the UCSF Mt. Zion clinic **You may NOT be eligible if...** - You do not meet all of the above criteria Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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