The Effectiveness of Dexmedetomidine as an Adjuvant for Bupivacaine Caudal Block in Pediatric Open Appendectomy Under General Anesthesia
Ain Shams University
60 participants
Aug 1, 2025
INTERVENTIONAL
Conditions
Summary
This study aims to evaluate if adding dexmedetomidine to bupivacaine in a caudal block can provide longer and better quality pain relief for children after open appendectomy surgery. The study will also assess the effect of this combination on the quality of recovery, including the incidence of emergence delirium, and its overall safety profile.
Eligibility
Inclusion Criteria1
- ASA (American Society of Anesthesiologists) physical status I or II.
Exclusion Criteria8
- Refusal of participation by the legal guardian.
- Known allergy or hypersensitivity to local anesthetics or dexmedetomidine.
- Coagulation disorder or receiving anticoagulant therapy.
- Active infection at or near the injection site.
- Significant anatomical abnormalities of the lumbosacral spine.
- Pre-existing neurological disorders, psychiatric disorders, or a history of convulsions.
- Anticipated surgery time of more than 2.5 hours.
- Patients with severe asthma or active wheezing.
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Interventions
Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 µg/kg of dexmedetomidine (diluted in 1 mL of normal saline).
Patients will receive a single-shot caudal block with 1 mL/kg of 0.25% bupivacaine mixed with 1 mL of normal saline
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT07088900