Pediatric Clinical Trials

460 recruitingLast updated: June 18, 2026

There are 460 actively recruiting pediatric clinical trials across 78 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Houston, Texas, United States, Boston, Massachusetts, United States, Los Angeles, California, United States. Updated daily from ClinicalTrials.gov.


Pediatric Trials at a Glance

460 actively recruiting trials for pediatric are listed on ClinicalTrialsFinder across 6 cities in 78 countries. The largest study group is Not Applicable with 193 trials, with the heaviest enrollment activity in Houston, Boston, and Los Angeles. Lead sponsors running pediatric studies include Duke University, St. Jude Children's Research Hospital, and Children's Hospital Los Angeles.

Treatments under study

About Pediatric Clinical Trials

Looking for clinical trials for Pediatric? There are currently 22 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Pediatric trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Pediatric clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 460 trials

Recruiting

NCI Childhood Cancer Data Initiative (CCDI) Led Pediatric, Adolescent, and Young Adult Rare Cancer Registry for Very Rare Solid Tumors

Solid TumorOther Solid TumorsVery Rare Tumors+2 more
National Cancer Institute (NCI)4,000 enrolled1 locationNCT07489378
Recruiting
Phase 1

A Phase I, First in Human Study of CBA-1205, Anti-DLK1 Monoclonal Antibody in Patients With Advanced Solid Tumors, Hepatocellular Carcinoma (HCC), Melanoma, and Pediatric Cancer

Solid TumorsHepatocellular Carcinoma (HCC)Malignant Melanoma+1 more
Chiome Bioscience Inc.66 enrolled5 locationsNCT06636435
Recruiting

Natural History and Biospecimen Acquisition for Children and Adults With Rare Solid Tumors

Solid TumorPediatric Solid TumorMalignant Solid Tumors+2 more
National Cancer Institute (NCI)10,000 enrolled3 locationsNCT03739827
Recruiting

Psychological Benefits of a Normalized Camping Experience for Children With Cancer

Pediatric Cancer
National Cancer Institute (NCI)5,000 enrolled1 locationNCT00001186
Recruiting
Phase 1

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more
National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting

Development of a Wearable Point of Care Monitoring Device for Pediatric Obstructive Sleep Apnea

Pediatric Obstructive Sleep Apnea
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)120 enrolled1 locationNCT05052216
Recruiting

Response to Influenza Vaccination in Pediatric Oncology Patients

Hematologic MalignancyPediatric CancerTransplant-Related Cancer
St. Jude Children's Research Hospital150 enrolled1 locationNCT05384288
Recruiting
Phase 1Phase 2

Phase 1/2 Study of Mirdametinib + Vinblastine for Newly Diagnosed/Previously Untreated PLGG + Activation of MAPK

Pediatric Low-grade Glioma
St. Justine's Hospital50 enrolled8 locationsNCT06666348
Recruiting
Phase 1

Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Pediatric Solid TumorPediatric Brain Tumor
Washington University School of Medicine20 enrolled1 locationNCT05521984
Recruiting
Phase 3

GB06 Phase III Trial for Pediatric Growth Hormone Deficiency

Growth Hormone Deficiency (GHD)Growth Hormone Deficiency in ChildrenGrowth Hormone Deficiency, Pediatric
Kexing Biopharm Co., Ltd.192 enrolled1 locationNCT07553351
Recruiting
Phase 4

Safety of Short-course of NSAIDs in Pediatric Patients With CKD

Chronic Kidney DiseasePediatric Urology
University of Colorado, Denver164 enrolled1 locationNCT06860711
Recruiting
Phase 3

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer117 enrolled132 locationsNCT07192952
Recruiting

A Study of HARMONIC 700 Shears With Advanced Hemostasis in Pediatric and Adult Surgical Procedures

Pediatric Surgical ProceduresAdult Surgical ProceduresAdult Gynecological Procedures+2 more
Ethicon Endo-Surgery165 enrolled9 locationsNCT06608485
Recruiting
Phase 3

Randomized Study in Children and Adolescents With Migraine: Acute Treatment

Pediatric Migraine
Pfizer2,100 enrolled246 locationsNCT04649242
Recruiting

A Repository to Study Host-Microbiome Interactions in Health and Disease

PregnancyHealthy (Controls)Pediatric Illnesses+1 more
National Institute of Allergy and Infectious Diseases (NIAID)600 enrolled1 locationNCT05656378
Recruiting

CAYA Cancer Prospective Cohort Study

CancerPediatric CancerAcute Lymphoblastic Leukemia ALL+1 more
Resonance, Inc.6,000 enrolled3 locationsNCT07632014
Recruiting
Phase 1

Safety and Feasibility of Intraoperative Visualization With Cytalux in Children

Metastatic SarcomaOsteosarcomaPulmonary Metastasis+2 more
Ann & Robert H Lurie Children's Hospital of Chicago10 enrolled1 locationNCT06235125
Recruiting
Not Applicable

Testing eSCCIP: An eHealth Psychosocial Intervention for English and Spanish Speaking Parents of Children With Cancer

Pediatric Cancer
Nemours Children's Clinic350 enrolled3 locationsNCT05294302
Recruiting

Multiomic Approach to Radioresistance of Ependymomas in Children and Adolescents

Pediatric Solid TumorEpendymoma of Brain
Institut Claudius Regaud370 enrolled1 locationNCT05151718