Pediatric Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Pediatric clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 152 trials

Recruiting

Data Collection Study of Pediatric and Adolescent Gynecology Conditions

Disorders of Sex Development (DSD)Pediatric and Adolescent Cancers of the Genital TractReproductive Endocrine Conditions in Puberty+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)11,000 enrolled1 locationNCT04717349
Recruiting
Not Applicable

Easing Scan Anxiety in Pediatric Oncology Caregivers Through Meditation-based Programs

Caregiver AnxietyCaregiver Anxiety Related to Cancer ImagingPediatric Oncology
Kimberley Roche160 enrolled1 locationNCT07420101
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Not Applicable

Proof-of-Concept Study of the SNOEZELEN Device on Anxiety Symptoms in Patients Hospitalized for Chemotherapy in a Pediatric Oncology Department

Pediatric CancerSnoezelenSymptomatologie Anxieuse+1 more
Centre Oscar Lambret20 enrolled1 locationNCT07202507
Recruiting
Phase 1Phase 2

Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor Patients

Hepatocellular CarcinomaRefractory Solid TumorPediatric Solid Tumor+3 more
St. Jude Children's Research Hospital64 enrolled2 locationsNCT05468359
Recruiting

Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease

Pediatric ALLCongenital Heart DiseaseHeart Transplantation
University of Alberta20 enrolled1 locationNCT06325280
Recruiting
Phase 1

Intra-Tumoral Injections of Natural Killer Cells for Recurrent Malignant Pediatric Brain Tumors

Pediatric Brain TumorRecurrent Pediatric Brain TumorPediatric Neoplasm
Sabine Mueller, MD, PhD24 enrolled8 locationsNCT05887882
Recruiting
Phase 1

Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Advanced Breast CancerAdvanced Solid TumorsMetastatic Pancreatic Cancer+3 more
National Cancer Institute (NCI)116 enrolled2 locationsNCT04222413
Recruiting
Not Applicable

HIIT in Pediatric Heart Transplant Recipients (MedBIKE™)

Pediatric ALLTransplant; Failure, Heart
University of Alberta10 enrolled1 locationNCT05451979
Recruiting

Thyroid Carcinoma in Cancer Patients Undergoing Radiotherapy

Thyroid CarcinomaPediatric Cancer
IRCCS Azienda Ospedaliero-Universitaria di Bologna2,550 enrolled2 locationsNCT07473518
Recruiting
Not Applicable

Study of the Efficacy of Moderate Sedation With Intra-NAsal Dexmedetomidine Monitored by EEG MOnitoring

Pediatric ALLProcedural Sedation and Analgesia
Centre Hospitalier Régional Metz-Thionville50 enrolled1 locationNCT06867289
Recruiting
Phase 1

CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and Lymphoma

Hematologic MalignancyRelapsed Pediatric ALLHematopoietic Cell Transplantation
St. Jude Children's Research Hospital60 enrolled1 locationNCT07257419
Recruiting

Pediatric Normative Markerless Movement Analysis

Pediatric ALLAdolescent
MultiCare Health System Research Institute40 enrolled1 locationNCT06249880
Recruiting
Not Applicable

AI Avatar Video vs. Tell-Show-Do for Reducing Anxiety and Improving Cooperation in Children During Local Anesthesia

AnxietyFearLocal Anesthesia+1 more
Saint-Joseph University70 enrolled1 locationNCT07449884
Recruiting
Phase 2

Orphan Indications for CD19 Redirected Autologous T Cells

Pediatric and Young Adult Patientswith Hypodiploid or t(17;19) B-ALLInfants With Very High Risk KMT2A B-ALLPatients With Central Nervous System Relapse Who Did Not Receive Cranial Radiation or Bone Marrow Transplantation
Stephan Grupp MD PhD133 enrolled1 locationNCT04276870
Recruiting
Phase 4

The Occurrence of Emergence Agitation in Pediatric Strabismus Surgery

Pediatric ALLEmergence DeliriumStrabismus
Konkuk University Medical Center76 enrolled1 locationNCT06035757
Recruiting
Phase 2

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

Liver CancerFibrolamellar CarcinomaHepatocellular Carcinoma, Childhood+1 more
Allison O'Neill, MD18 enrolled5 locationsNCT04134559
Recruiting
Not Applicable

High-Intensity Interval Exercise in Young Adult Survivors of Pediatric Brain Tumors: A Pilot Feasibility Study

Pediatric Brain Tumor
Dana-Farber Cancer Institute30 enrolled1 locationNCT05740839
Recruiting
Phase 1Phase 2

Lurbinectedin in FET-Fused Tumors

Ewing SarcomaPediatric CancerDesmoplastic Small Round Cell Tumor+1 more
Children's Hospital of Philadelphia63 enrolled6 locationsNCT05918640
Recruiting
Early Phase 1

Feasibility Trial of Sodium-GLucose coTransporter 2 INhibitors in Pediatric Chronic KIDney DiSease

Chronic Kidney DiseasesPediatric Kidney Disease
Ann & Robert H Lurie Children's Hospital of Chicago40 enrolled1 locationNCT06430684