Colon-delivered Riboflavin and Gut Microbiota Composition
The Benefit of Colon-delivered Riboflavin (Riboflavin-cd) vs. Conventional Riboflavin on Gut Microbiota Composition and Metabolic Output in Healthy Aging Subjects - a Pilot Proof of Concept Study
dsm-firmenich Switzerland AG
90 participants
Jul 18, 2025
INTERVENTIONAL
Conditions
Summary
Recent studies suggest B-vitamins such as riboflavin to possess prebiotic-like effects. However, there is still a lack of understanding of the exact host health benefits vs. conventional systemically available vitamin forms. The present study explores the benefit of colon-delivered vitamin B2 vs. conventional vitamin B2 in comparison to placebo in an aging population on gut microbiota and metabolic activity as well as gut health.
Eligibility
Plain Language Summary
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Interventions
10 mg of colon-delivered riboflavin
10 mg of conventional riboflavin
10 mg microcrystalline cellulose
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07093463