RecruitingNot ApplicableNCT07096336

Effect of Vitamin D3 on Brain Waves in Male Parkinson's Patients With Low Vitamin D: A qEEG Study

Effect of Vitamin D3 Supplementation on Brain Waves in Male Parkinson's Disease Patients With Hypovitaminosis D : A Quantitative Electroencephalogram Analysis


Sponsor

Bangladesh Medical University

Enrollment

15 participants

Start Date

Jul 15, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is an experimental study (Interventional self-controlled trial, pretest-posttest design). The goal of this clinical trial is to evaluate the effect of vitamin D3 supplementation on quantitative EEG in male Parkinson's disease patients with hypovitaminosis D. The main question it aims to answer is: Vitamin D3 supplementation has effect on brain waves in male Parkinson's disease patients with hypovitaminosis D. Researcher will compare the effect of vitamin D3 supplementation on brain waves in male Parkinson's disease patients with hypovitaminosis D with their pre intervention ( baseline ) condition on brain waves to assess whether there will be any improvement of brain electrical activity by quantitative electroencephalogram (QEEG). Participants will : Take vitamin D3 orally for 8 weeks (50,000 IU/week) Visit the medical university after 8 weeks for evaluation of serum 25(OH)D level and QEEG Must bring the empty strips of vitamin D supplement with them during their visit.


Eligibility

Sex: MALEMin Age: 51 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether taking vitamin D3 supplements changes brain wave patterns (measured by a brain EEG test) in men with Parkinson's disease who have low vitamin D levels. Low vitamin D is common in Parkinson's patients, and researchers want to understand if correcting this deficiency affects brain activity. **You may be eligible if...** - You are a man between 51 and 70 years old - You have Parkinson's disease at stage 3 or lower on the Hoehn and Yahr scale (mild to moderate) - Your vitamin D blood level is below 30 ng/mL (considered low) - You have a normal body weight (BMI 18.5–24.9) - You are currently taking levodopa (a standard Parkinson's medication) **You may NOT be eligible if...** - You are already taking vitamin D3 supplements - You take medications known to affect brain activity or EEG results (e.g., sedatives, antidepressants, antipsychotics, or alcohol) - You have other neurological conditions (epilepsy, migraine), heart disease, respiratory disease, or serious psychiatric illness - You have high calcium levels, kidney disease, liver disease, or uncontrolled thyroid or diabetes conditions - You are an active smoker Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTvitamin D3 capsule

Administration of vitamin D3 capsule 50,000 IU/week for 8 weeks


Locations(1)

Bangladesh medical university

Dhaka, Shahbag, Bangladesh

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NCT07096336


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