RecruitingNCT07098858

The WiSE®-UP Registry (The WiSE System Utilization & Performance Registry)

Sponsor

EBR Systems, Inc.

Enrollment

320 participants

Start Date

Nov 3, 2025

Study Type

OBSERVATIONAL

Conditions

Heart Failure

Summary

Observe to understand product performance, including patient safety, clinical outcomes, and CRT response information associated with the use of the market-released WiSE System

Eligibility

Inclusion Criteria6

Patient or legally authorized representative can provide written authorization and/or consent per institution requirements.
Patient is intended to receive a WiSE System and passed the acoustic window screening
Patient who is, or will be, accessible for follow-up.
Participation is not excluded by local law.
Patient is not enrolled in a concurrent drug and/or device study that may confound the Registry results.
Patient life expectancy \>1 year.

Interventions

DEVICEThe Wise System

The WiSE CRT System is an implantable cardiac system to provide left ventricular (LV) pacing stimulation in conjunction with a co-implanted system that provides right ventricular (RV) stimulation. In combination, the devices deliver biventricular (BiV) pacing.