RecruitingPhase 4NCT07101250

Preoperative Acetazolamide

Preoperative Acetazolamide for Improved Pain Control Following Laparoscopic Hysterectomy


Sponsor

Prisma Health-Upstate

Enrollment

100 participants

Start Date

Oct 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this randomized study looks at whether giving patients a medicine called acetazolamide (also called Diamox) before they have laparoscopic hysterectomy may decrease postoperative pain. Researchers will compare acetazolamide to a placebo or inactive drug, to see if acetazolamide helps the pain that may occur after surgery from the gas used in the abdomen during the laparoscopic procedure. Patients will be asked to rate their pain before surgery and after surgery through 24 hours.


Eligibility

Sex: FEMALEMin Age: 21 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Acetazolamide 500 MG Extended Release Oral Capsule and a drug called Placebo for people with post operative pain, referred pain, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 21 Years to 65 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGAcetazolamide 500 MG Extended Release Oral Capsule

Active Drug

DRUGPlacebo

Inactive Drug


Locations(1)

Prisma Health

Greenville, South Carolina, United States

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NCT07101250


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