RecruitingPhase 3NCT07102628

Evaluation of Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes

A Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy and Safety of Early in Hospital Initiation of Inclisiran Treatment in Patients With Acute Coronary Syndromes: Victorion - RIDES


Sponsor

Novartis Pharmaceuticals

Enrollment

300 participants

Start Date

Oct 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this trial is to learn about the effects of inclisiran in people with serious heart conditions (acute coronary syndromes), when this treatment is started early after hospital admission. To do this, researchers will test the effects of inclisiran compared to placebo, when given with standard treatment.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Inclisiran and a drug called Placebo for people with acute coronary syndrome. The study is currently recruiting participants at 63 locations. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGPlacebo

The participants will receive placebo subcutaneous at randomization (Day 1, Baseline visit) and Day 90

DRUGInclisiran

The participants will receive Inclisiran sodium 300 mg subcutaneous at randomization (Day 1, Baseline visit) and Day 90


Locations(63)

Novartis Investigative Site

Clayton, Victoria, Australia

Novartis Investigative Site

Montreal, Quebec, Canada

Novartis Investigative Site

Québec, Quebec, Canada

Novartis Investigative Site

Beijing, China, China

Novartis Investigative Site

Guangzhou, Guangdong, China

Novartis Investigative Site

Luoyang, Henan, China

Novartis Investigative Site

Xuzhou, Jiangsu, China

Novartis Investigative Site

Nanchang, Jiangxi, China

Novartis Investigative Site

Wenzhou, Zhejiang, China

Novartis Investigative Site

Beijing, China

Novartis Investigative Site

Beijing, China

Novartis Investigative Site

Fuzhou, China

Novartis Investigative Site

Guangzhou, China

Novartis Investigative Site

Guangzhou, China

Novartis Investigative Site

Jining, China

Novartis Investigative Site

Shanghai, China

Novartis Investigative Site

Shanghai, China

Novartis Investigative Site

Tianjin, China

Novartis Investigative Site

Chambray-lès-Tours, France

Novartis Investigative Site

Montpellier, France

Novartis Investigative Site

Nantes, France

Novartis Investigative Site

Pessac, France

Novartis Investigative Site

Poitiers, France

Novartis Investigative Site

Leipzig, Saxony, Germany

Novartis Investigative Site

Coburg, Germany

Novartis Investigative Site

Erfurt, Germany

Novartis Investigative Site

Essen, Germany

Novartis Investigative Site

Hennigsdorf, Germany

Novartis Investigative Site

Kiel, Germany

Novartis Investigative Site

Hong Kong, Hong Kong, Hong Kong

Novartis Investigative Site

Hong Kong, Hong Kong

Novartis Investigative Site

Pécs, Baranya, Hungary

Novartis Investigative Site

Debrecen, Hajdu Bihar Megye, Hungary

Novartis Investigative Site

Budapest, Hungary

Novartis Investigative Site

Budapest, Hungary

Novartis Investigative Site

Miskolc, Hungary

Novartis Investigative Site

Belagavi, Karnataka, India

Novartis Investigative Site

Mumbai, Maharashtra, India

Novartis Investigative Site

Nashik, Maharashtra, India

Novartis Investigative Site

Bikaner, Rajasthan, India

Novartis Investigative Site

Chikushino-shi, Fukuka, Japan

Novartis Investigative Site

Kitakyushu, Fukuoka, Japan

Novartis Investigative Site

Kamakura, Kanagawa, Japan

Novartis Investigative Site

Sagamihara, Kanagawa, Japan

Novartis Investigative Site

Bunkyo Ku, Tokyo, Japan

Novartis Investigative Site

Gdansk, Poland

Novartis Investigative Site

Katowice, Poland

Novartis Investigative Site

Krakow, Poland

Novartis Investigative Site

Opole, Poland

Novartis Investigative Site

Seoul, Seoul, South Korea

Novartis Investigative Site

Seoul, South Korea

Novartis Investigative Site

Santiago Compostela, A Coruna, Spain

Novartis Investigative Site

Huelva, Andalusia, Spain

Novartis Investigative Site

El Palmar, Murcia, Spain

Novartis Investigative Site

Las Palmas GC, Spain

Novartis Investigative Site

Madrid, Spain

Novartis Investigative Site

Madrid, Spain

Novartis Investigative Site

Salamanca, Spain

Novartis Investigative Site

Seville, Spain

Novartis Investigative Site

Valencia, Spain

Novartis Investigative Site

Bern, Switzerland

Novartis Investigative Site

Geneva, Switzerland

Novartis Investigative Site

Lucerne, Switzerland

View Full Details on ClinicalTrials.gov

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NCT07102628


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