Mechanism of Red Yeast Rice Regulating Intestinal Indole Metabolism Pathway to Improve Chronic Inflammation in Polycystic Ovary Syndrome

This study is investigating how red yeast rice — a traditional supplement — may help reduce chronic inflammation in women with polycystic ovary syndrome (PCOS) by changing how the gut microbiome processes certain compounds called indoles. The goal is to understand if this supplement can improve PCOS symptoms through gut health. **You may be eligible if:** - You are a woman between 18 and 40 years old - You have been diagnosed with PCOS (meeting at least 2 of 3 Rotterdam criteria: irregular ovulation, signs of excess androgens, or polycystic ovaries on ultrasound) - You have agreed to participate and understand what the study involves **You may NOT be eligible if:** - You are pregnant - You have serious infections or severe organ disease - You have taken antibiotics or probiotics/prebiotics recently - You have taken medications that significantly affect gut bacteria - You have another hormonal disorder that might explain your symptoms Talk to your doctor to see if this trial is right for you.