RecruitingNot ApplicableNCT07110896

Study Evaluating the Effect of Humiome® Post LB on Stress, Anxiety, and Cognition in Aging Adults

A Randomized, Placebo-controlled, Double-blind Clinical Study to Evaluate the Effect of Humiome® Post LB on Stress, Anxiety, and Cognition in Aging Adults


Sponsor

dsm-firmenich Switzerland AG

Enrollment

236 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

To assess the effect of 3 months of daily consumption of a postbiotic (inactivated lactic acid bacteria) Humiome® Post LB on stress measured by the Depression Anxiety Stress Scale-21 (DASS-21) adjusted on baseline in study participants when compared to placebo


Eligibility

Min Age: 50 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a probiotic supplement called Humiome Post LB to see if it can reduce stress, anxiety, and mild memory complaints in older adults. Gut health is increasingly linked to brain function, and this trial aims to measure whether this specific probiotic helps with mood and thinking. **You may be eligible if...** - You are between 50 and 75 years old - You have a body mass index (BMI) between 18.5 and 32 - You are generally in good health - You have mild to moderate memory complaints or stress/anxiety symptoms (based on a standard questionnaire score of 42-60 on the DASS-21) - You are willing to maintain your regular diet, exercise, and medication habits throughout the study **You may NOT be eligible if...** - You have a diagnosed psychiatric or neurological condition (such as epilepsy, dementia, or major depression) - You have taken probiotics or certain supplements recently - You have a chronic gastrointestinal condition - You have a compromised immune system - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTHumiome Post LB (Postbiotic)

Heat-inactivated lactobacilli with fermented medium (a postbiotic) in 340mg powder format

DIETARY_SUPPLEMENTPlacebo

Microcrystalline cellulose, 340mg powder format


Locations(3)

Biofortis

Paris, France

Biofortis

Saint-Herblain, France

analyze & realize GmbH

Berlin, Germany

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NCT07110896


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