RecruitingNCT07112924

CCM OPEN HF Registry

CCM Technologies OPEN HF Registry: Observational Patient EvaluatioN of CCM® Therapy for Heart Failure


Sponsor

Impulse Dynamics

Enrollment

5,500 participants

Start Date

Nov 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is an open-ended real-world registry study following patients with heart failure who have received or are planned to receive a Cardiac Contractility Modulation (CCM) device. CCM is a small implanted device (similar in concept to a pacemaker) that sends precisely timed electrical signals to strengthen the heart's pumping ability without pacing the heart. The registry aims to understand long-term safety, effectiveness, and quality-of-life outcomes in everyday clinical practice. **You may be eligible if...** - You have been implanted with, or are scheduled to receive, a CCM device made by Impulse Dynamics for heart failure - You are willing and able to provide informed consent, including consent for your data to be used in research and publications - You are committed to attending follow-up visits and taking your medications as directed **You may NOT be eligible if...** - Your doctors believe you are unlikely to follow through with follow-up appointments or medication adherence - You have a mechanical tricuspid valve (an artificial replacement of the heart's tricuspid valve) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(28)

Cardiovascular Associates of Mesa

Mesa, Arizona, United States

University of Arizona and Banner University Medical Center Phoenix

Phoenix, Arizona, United States

HonorHealth Research Institute

Phoenix, Arizona, United States

Peak Heart and Vascular

Surprise, Arizona, United States

AdventHealth Orlando

Orlando, Florida, United States

AdventHealth Tampa

Tampa, Florida, United States

University of Kansas Medical Center

Kansas City, Kansas, United States

Massachusetts General Hospital

Boston, Massachusetts, United States

University of Michigan

Ann Arbor, Michigan, United States

Henry Ford Providence Hospital

Novi, Michigan, United States

Trinity Ann Arbor d/b/a Michigan Heart Ann Arbor

Ypsilanti, Michigan, United States

Minneapolis Heart Institute Research Foundation

Minneapolis, Minnesota, United States

Saint Luke's Hospital Mid America Heart Institute

Kansas City, Missouri, United States

Saint Luke's Hospital of Kansas City

Kansas City, Missouri, United States

Cardiovascular Specialists of New England Research Foundation

Londonderry, New Hampshire, United States

Deborah Heart and Lung Center

Browns Mills, New Jersey, United States

Hackensack University Medical Center

Hackensack, New Jersey, United States

Rutgers New Jersey Medical School & University Hospital

Newark, New Jersey, United States

Providence St. Vincent Medical Center

Portland, Oregon, United States

Legacy Medical Group Cardiology

Portland, Oregon, United States

Reading Hospital

West Reading, Pennsylvania, United States

The Stern Cardiovascular Foundation, Inc

Germantown, Tennessee, United States

David Turbay, MD

El Paso, Texas, United States

Texan Cardiovascular Institute

El Paso, Texas, United States

CHRISTUS Trinity Mother Frances Health System

Tyler, Texas, United States

Centra Health, Inc. dba Stroobants Cardiovascular Center

Lynchburg, Virginia, United States

PeaceHealth Southwest Medical Center

Vancouver, Washington, United States

Advocate Aurora Health-St. Lukes

Milwaukee, Wisconsin, United States

View Full Details on ClinicalTrials.gov

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NCT07112924


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