RecruitingNot ApplicableNCT07119840

Comparison Of Clinical Effects Of Listerine And Chlorhexidine Mouth Wash In Patients Undergoing Fixed Orthodontic Treatment


Sponsor

Khyber Medical University Peshawar

Enrollment

60 participants

Start Date

Aug 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This randomized clinical trial aims to compare the effectiveness of Listerine and Chlorhexidine mouthwashes in improving periodontal health in patients undergoing fixed orthodontic treatment. Gingival Index and Plaque Index will be assessed at baseline, 2 weeks, and 4 weeks.


Eligibility

Min Age: 13 YearsMax Age: 40 Years

Inclusion Criteria3

  • Aged 13-40 years
  • Permanent dentition (including first molars)
  • Willing to undergo orthodontic treatment and follow instructions

Exclusion Criteria6

  • Systemic illness (e.g., diabetes, heart disease, hepatitis)
  • Pregnant/lactating females
  • Tobacco use
  • History of allergies to mouthwash/toothpaste
  • Use of mouthwash in past 3 months
  • Abnormal oral morphology or parafunctional habits

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Interventions

DRUGListerine Mouthwash Product

Participants in this group will receive Listerine mouthwash containing essential oils (menthol, thymol, eucalyptol, and methyl salicylate). They will be instructed to rinse once daily with 10 ml of the solution for 30 seconds after brushing, over a period of 4 weeks. The mouthwash will be dispensed in unlabelled bottles to maintain blinding. Standard oral hygiene instructions will be given.

DRUGChlorhexidine mouthwash

Participants in this group will receive Chlorhexidine mouthwash at a concentration of 0.12%. They will be instructed to rinse once daily with 10 ml of the solution for 30 seconds after brushing, over a period of 4 weeks. The mouthwash will be dispensed in unlabelled bottles to maintain blinding. Standard oral hygiene instructions will be given.


Locations(1)

Saidu College of Dentistry

Swāt, KPK, Pakistan

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NCT07119840


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