RecruitingNot ApplicableNCT07121140

Home Blood Transfusions

A Pilot Study of Home Blood Transfusions for Patient With Cancer Who Have Transfusion Dependent Cytopenias


Sponsor

Thomas Jefferson University

Enrollment

30 participants

Start Date

Jun 3, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This is a pilot single arm study to evaluate the feasibility and acceptability of a home blood transfusion program. Patients will be enrolled with hematologic malignancies and other bone marrow failure syndromes who are transfusion dependent and interested in a home blood transfusion program. Participants enrolled in the study will receive 1-5 units of blood products at home. Data on barriers to administration will be recorded. Surveys and qualitative interviews will be completed to better understand acceptability of the program.


Eligibility

Min Age: 18 Years

Inclusion Criteria7

  • Provide signed and dated informed consent form Willing to comply with all study procedures and be available for the duration of the study
  • Male or female, over the age of 18
  • Must meet definition of transfusion dependence (require at least 2 blood product transfusions over a 28-day period)
  • Receive their cancer care at SKCCC
  • Have a history of blood product transfusions and NO history of transfusion reactions,
  • Live within a 30-mile range of the Center City SKCCC location.
  • Must be willing to allow people into the home

Exclusion Criteria9

  • An individual who meets any of the following criteria will be excluded from participation in this study:
  • Patients who have a history of a transfusion reaction
  • Heart failure as defined by AHA stage C or NYHA Class II-IV
  • Non-English or Spanish speaking
  • Are unhoused
  • Are incarcerated
  • Have poor venous access
  • Diagnosis of Solid Tumor malignancy
  • Women who are pregnant

Interventions

PROCEDUREHome Blood Transfusion

Participants will be provided with transfusion of blood products, specifically red blood cells and platelets, in the home setting.


Locations(1)

Thomas Jefferson University Hospital

Philadelphia, Pennsylvania, United States

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NCT07121140


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