RecruitingNot ApplicableNCT07123909

Studies on Adsorption International Learning Initiative Global

The Use of Sorption Technologies in Patients Receiving Program Hemodialysis With Inflammatory Syndrome


Sponsor

Botkin Hospital

Enrollment

60 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Use of sorption technologies in patients undergoing maintenance hemodialysis with inflammatory syndrome and clinical manifestations of uremia


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Adequate dialysis defined by a KT/V index ≥ 1.4
  • No active inflammatory process or infection
  • Age ≥ 18 years
  • Receiving standard hemodialysis regimen three times weekly, at least 4 hours per session
  • Participants with elevated interleukin-6 (IL-6) and/or C-reactive protein (CRP) levels exceeding local laboratory reference values

Exclusion Criteria4

  • Current use of steroids or immunosuppressive therapy
  • History of kidney transplantation
  • Diagnosis of cancer
  • Pregnancy

Interventions

DEVICEPatients will undergo a combined hemodialysis and hemosorption procedure. The study cartridge for hemosorption by Jafron HA130 contains the original adsorbing material.

The test cartridge will be used in addition to the ongoing program hemodialysis three times a week in the first month, twice a week in the next month, once a week in the third month


Locations(1)

Botkin Hospital

Moscow, Russia

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NCT07123909


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