RecruitingNot ApplicableNCT07125001

Mango Intake and Gut and Cardiometabolic Health in Hispanic/Latino Adolescents

The Influence of Mango-Derived Intestinal Microbial Metabolites on Gut Permeability, Inflammation, and Cardiometabolic Health Markers in Hispanic/Latino Adolescents


Sponsor

University of California, Davis

Enrollment

25 participants

Start Date

Oct 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Mangos contain a number of nutrients that may improve gut and metabolic health. The purpose of this research is to see how eating mangos every day for 4 weeks instead of snacks high in calories and low in nutrients such as cookies, crackers, chips, and candy can impact adolescent health.


Eligibility

Min Age: 12 YearsMax Age: 19 Years

Inclusion Criteria7

  • \- Male or Female 12-19 years old
  • BMI ≥ 85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
  • Self-reported Hispanic/Latino
  • Subject is willing and able to comply with the study protocols
  • Subject is willing to consume the test products
  • Female-specific criteria: if menstruating, eumenorrheic (regular monthly menstrual cycles of 25-30-days in length)
  • Access to a smartphone or tablet at least 1x / day and willing to take pictures associated with the products to be consumed in the study

Exclusion Criteria12

  • \- Reported food allergies.
  • Currently taking prescription drugs, with the exception of asthma inhalers, which are allowed
  • BMI \<85th percentile (https://www.bcm.edu/bodycomplab/BMIapp/BMI-calculator-kids.html)
  • Current participation in a moderate or high-intensity daily exercise routine
  • Self-reported disease, serious illness, or who are currently under acute medical care.
  • Currently taking prescription drugs.
  • Any supplement use, including multi-vitamin/ mineral, herbal, plant or botanical, fish oil, and oil supplements, and not willing to discontinue before starting the study.
  • Vegetarian or vegan diet
  • Self-reported malabsorption or gastrointestinal issues
  • Fruit and vegetable intake exceeding daily recommendations of 5 servings
  • Smoking (vaping, conventional nicotine-containing products or marijuana)
  • Current enrollee in a clinical research study

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Interventions

OTHERAtaulfo mango

4 weeks of Ataulfo mango intake


Locations(1)

Academic Surge; Ragle Human Nutrition Research Center

Davis, California, United States

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NCT07125001


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