RecruitingNCT07125209

Cognitive Impact of Neoadjuvant Chemotherapy for Ovarian Cancer


Sponsor

University of Wisconsin, Madison

Enrollment

18 participants

Start Date

Apr 28, 2026

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this research is to assess several components of cognition in patients recently diagnosed with advanced epithelial ovarian cancer and who will be undergoing neoadjuvant chemotherapy for treatment of the cancer. 18 participants will be enrolled and can expect to be on study for approximately 10 months.


Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining how neoadjuvant chemotherapy (chemotherapy given before surgery) affects memory, thinking, and cognitive function in women with suspected ovarian cancer, to better understand what is sometimes called 'chemo brain.' **You may be eligible if...** - You are 18 years or older - You have been diagnosed with — or are suspected to have — epithelial ovarian cancer - You are scheduled to receive chemotherapy before surgery **You may NOT be eligible if...** - Your biopsy later confirms a cancer type other than epithelial ovarian cancer (you would be removed from the study) - You have significant pre-existing cognitive impairment - You are not scheduled for neoadjuvant chemotherapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERPatient Reported Outcomes Assessment

Functional Assessment of Cancer Therapy - Ovarian (FACT-O) and Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) will be used to assess patient reported outcomes.

OTHERCognitive and General Health Assessments

* Rey Verbal Learning Test * Trail Making Test * Patient Health Questionnaire (PHQ-2) * Mini Mental State Exam (MMSE) * Controlled Oral Word Association Test of the Multilingual Aphasia Examination


Locations(1)

UW Carbone Cancer Center

Madison, Wisconsin, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT07125209


Related Trials