Moderate-Intensity Exercise and Pain Sensitization in Breast Cancer Survivors: A Case-Based Study
Universidad Rey Juan Carlos
10 participants
Aug 23, 2025
INTERVENTIONAL
Conditions
Summary
The aim of this study was to evaluate the feasibility, safety, and acceptability of a supervised, combined moderate-intensity aerobic and resistance training program designed to reduce pain sensitization in BCS with persistent pain. Secondary objectives included assessing changes in pain intensity, somatosensory sensitivity, and temporal summation, while tertiary objectives focused on improvements in quality of life and functional capacity.
Eligibility
Inclusion Criteria3
- Adult women diagnosed with stage I-III breast cancer
- Completion of active treatment (surgery, chemotherapy, and/or radiotherapy) at least 6 months prior to enrollment
- Presence of persistent pain or altered sensation in the upper quadrant of the affected limb related to oncologic treatment
Exclusion Criteria7
- Bilateral breast cancer
- Locoregional recurrence
- Other malignancies
- Pre-existing pain not related to cancer treatment
- Neurological or cognitive disorders
- Non-Spanish speakers
- Contraindications to moderate-intensity physical activity
Interventions
The experimental group completed a five-week supervised program combining moderate-intensity aerobic and resistance training (150 min/week). Intensity was monitored using the Borg and OMNI-Res scales after familiarization sessions. Adherence was encouraged through reminders, motivational messages, and follow-ups. Unlike prior studies, this intervention focused specifically on neurophysiological pain modulation. Sessions included step-based aerobic exercises and resistance training with elastic bands under safety protocols.
Locations(1)
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NCT07128030