Two-fraction Proton Therapy With MRI Guidance for Prostate Cancer: A Phase II Trial

This study is testing a shorter prostate cancer radiation treatment using proton therapy delivered in just two sessions, guided by MRI scans, in men with low- or intermediate-risk prostate cancer. **You may be eligible if...** - You are under 18 years old — NOTE: the inclusion criteria states "Men aged < 18 years" which appears to be a data entry error; please confirm with the study team - You have been diagnosed with low- or intermediate-risk prostate cancer confirmed by biopsy - Your overall health is good (ECOG score less than 2) - You are able to undergo MRI scans **You may NOT be eligible if...** - You have a history of inflammatory bowel disease or another cancer - You have had prior pelvic radiation, chemotherapy, prostatectomy, cryosurgery, or focused ultrasound for prostate cancer - You have a history of bladder neck or urethral stricture - You have had a previous TURP (a procedure to unblock urine flow) Talk to your doctor to see if this trial is right for you.